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Spatiotemporal and genetic regulation of A-to-I editing throughout human brain development

Posttranscriptional RNA modifications by adenosine-to-inosine (A-to-I) editing are abundant in the brain, yet elucidating functional sites remains challenging. To bridge this gap, we investigate spatiotemporal and genetically regulated A-to-I editing sites across prenatal and postnatal stages of hum...

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Detalles Bibliográficos
Autores principales: Cuddleston, Winston H., Fan, Xuanjia, Sloofman, Laura, Liang, Lindsay, Mossotto, Enrico, Moore, Kendall, Zipkowitz, Sarah, Wang, Minghui, Zhang, Bin, Wang, Jiebiao, Sestan, Nenad, Devlin, Bernie, Roeder, Kathryn, Sanders, Stephan J., Buxbaum, Joseph D., Breen, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704047/
https://www.ncbi.nlm.nih.gov/pubmed/36323256
http://dx.doi.org/10.1016/j.celrep.2022.111585