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Enhancement of the anticancer effect of atorvastatin-loaded nanoemulsions by improving oral absorption via multivalent intestinal transporter-targeting lipids

Atorvastatin (ATV) has attracted considerable attention as a potential therapeutic agent for cancer because it inhibits cancer cell proliferation by suppressing the mevalonate pathway. However, because of its low oral absorption, high doses of ATV are required for chemotherapeutic applications. In t...

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Detalles Bibliográficos
Autores principales: Subedi, Laxman, Pandey, Prashant, Khadka, Bikram, Shim, Jung-Hyun, Cho, Seung-Sik, Kweon, Seho, Byun, Youngro, Kim, Ki-Taek, Park, Jin Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704079/
https://www.ncbi.nlm.nih.gov/pubmed/36419245
http://dx.doi.org/10.1080/10717544.2022.2149896