Cargando…

The effect of crRNA–target mismatches on cOA-mediated interference by a type III-A CRISPR-Cas system

CRISPR systems elicit interference when a foreign nucleic acid is detected by its ability to base-pair to crRNA. Understanding what degree of complementarity between a foreign nucleic acid and crRNA is required for interference is a central question in the study of CRISPR systems. A clear descriptio...

Descripción completa

Detalles Bibliográficos
Autores principales: Nasef, Mohamed, Khweis, Sarah A., Dunkle, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704408/
https://www.ncbi.nlm.nih.gov/pubmed/36424814
http://dx.doi.org/10.1080/15476286.2022.2150812