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The effect of crRNA–target mismatches on cOA-mediated interference by a type III-A CRISPR-Cas system
CRISPR systems elicit interference when a foreign nucleic acid is detected by its ability to base-pair to crRNA. Understanding what degree of complementarity between a foreign nucleic acid and crRNA is required for interference is a central question in the study of CRISPR systems. A clear descriptio...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704408/ https://www.ncbi.nlm.nih.gov/pubmed/36424814 http://dx.doi.org/10.1080/15476286.2022.2150812 |