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Specificity and Breadth of the Neutralizing Antibody Response to a Live-Attenuated Tetravalent Dengue Vaccine

BACKGROUND: An effective dengue vaccine should ideally induce broadly neutralizing antibody (nAb) responses against all 4 dengue virus (DENV) serotypes. METHODS: We characterized the specificity and breadth of the nAb response to TAK-003, a live-attenuated tetravalent dengue vaccine, in serum sample...

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Detalles Bibliográficos
Autores principales: DeMaso, Christina R, Karwal, Lovkesh, Zahralban-Steele, Melissa, Dominguez, David, Springer, Zhang-Li, Kaiser, Maima, Palani, Sunil, Rindfleisch, Tim, Bohning, Kelly, Hather, Greg, Das, Subash, Sharma, Mayuri, Dean, Hansi J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704433/
https://www.ncbi.nlm.nih.gov/pubmed/35771658
http://dx.doi.org/10.1093/infdis/jiac272