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Assessment of flomoxef combined with amikacin in a hollow-fibre infection model for the treatment of neonatal sepsis in low- and middle-income healthcare settings

BACKGROUND: Annual mortality from neonatal sepsis is an estimated 430 000–680 000 infants globally, most of which occur in low- and middle-income countries (LMICs). The WHO currently recommends a narrow-spectrum β-lactam (e.g. ampicillin) and gentamicin as first-line empirical therapy. However, avai...

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Detalles Bibliográficos
Autores principales: Darlow, Christopher A, McEntee, Laura, Johnson, Adam, Farrington, Nicola, Unsworth, Jennifer, Jimenez-Valverde, Ana, Jagota, Bhavana, Kolamunnage-Dona, Ruwanthi, Da Costa, Renata M A, Ellis, Sally, Franceschi, François, Sharland, Mike, Neely, Michael, Piddock, Laura, Das, Shampa, Hope, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704437/
https://www.ncbi.nlm.nih.gov/pubmed/36177766
http://dx.doi.org/10.1093/jac/dkac323