Keeping RelApse in Chk: molecular mechanisms of Chk1 inhibitor resistance in lymphoma

Chk1 is a member of the DNA damage response pathway, whose loss leads to replication stress and genome instability. Because of its protective role against lethal levels of DNA replication stress, Chk1 has been studied as a valuable and intriguing target for cancer therapy. However, one of the most p...

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Detalles Bibliográficos
Autores principales: Black, Elizabeth M., Joo, Yoon Ki, Kabeche, Lilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704517/
https://www.ncbi.nlm.nih.gov/pubmed/36416754
http://dx.doi.org/10.1042/BCJ20220461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704517/
https://www.ncbi.nlm.nih.gov/pubmed/36416754
http://dx.doi.org/10.1042/BCJ20220461

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