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Mechanistic insights into protein folding by the eukaryotic chaperonin complex CCT

The cytosolic chaperonin CCT is indispensable to eukaryotic life, folding the cytoskeletal proteins actin and tubulin along with an estimated 10% of the remaining proteome. However, it also participates in human diseases such as cancer and viral infections, rendering it valuable as a potential thera...

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Detalles Bibliográficos
Autores principales: Smith, Theresa M., Willardson, Barry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704529/
https://www.ncbi.nlm.nih.gov/pubmed/36196890
http://dx.doi.org/10.1042/BST20220591