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Mechanistic insights into protein folding by the eukaryotic chaperonin complex CCT
The cytosolic chaperonin CCT is indispensable to eukaryotic life, folding the cytoskeletal proteins actin and tubulin along with an estimated 10% of the remaining proteome. However, it also participates in human diseases such as cancer and viral infections, rendering it valuable as a potential thera...
Autores principales: | Smith, Theresa M., Willardson, Barry M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704529/ https://www.ncbi.nlm.nih.gov/pubmed/36196890 http://dx.doi.org/10.1042/BST20220591 |
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