Cargando…

Transcriptional plasticity of fibroblasts in heart disease

Cardiac fibroblasts play an essential role in maintaining the structural framework of the heart. Upon stress, fibroblasts undergo a cell state transition to activated fibroblasts (also referred to as myofibroblasts), a highly synthetic cell type that proliferates, migrates, and secrets both extracel...

Descripción completa

Detalles Bibliográficos
Autores principales: Micheletti, Rudi, Alexanian, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704531/
https://www.ncbi.nlm.nih.gov/pubmed/36281993
http://dx.doi.org/10.1042/BST20210864