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MiR-302d inhibits TGFB-induced EMT and promotes MET in primary human RPE cells

PURPOSE: Transforming growth factor-beta (TGFB)-mediated epithelial-mesenchymal transition (EMT) plays a crucial role in the pathogenesis of retinal fibrosis, which is one of the leading causes of impaired vision. Current approaches to treating retinal fibrosis focus, among other things, on inhibiti...

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Detalles Bibliográficos
Autores principales: Hu, Xiaonan, Binter, Maximilian, Hufendiek, Karsten, Tode, Jan, Framme, Carsten, Fuchs, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704570/
https://www.ncbi.nlm.nih.gov/pubmed/36441751
http://dx.doi.org/10.1371/journal.pone.0278158