Cargando…
CRISPR/Cas9-mediated knock-in strategy at the Rosa26 locus in cattle fetal fibroblasts
The genetic modification of cattle has many agricultural and biomedical applications. However, random integration often leads to the unstable or differentially expression of the exogenous genes, which limit the application and development of transgenic technologies. Finding a safe locus suitable for...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704577/ https://www.ncbi.nlm.nih.gov/pubmed/36441701 http://dx.doi.org/10.1371/journal.pone.0276811 |