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Thymic involution caused by repeated cocaine administration includes apoptotic cell loss followed by ectopic adipogenesis

Cocaine abuse has a negative impact on the immune system. To investigate the adverse effects of binge cocaine administration on lymphoid organs such as thymus and spleen, we examined the effects of repeated intravenous (i.v.) administration of cocaine on rats. Sprague Dawley rats (male, 8 weeks old)...

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Detalles Bibliográficos
Autores principales: Unuma, Kana, Kaga, Homare, Funakoshi, Takeshi, Nomura, Moeka, Aki, Toshihiko, Uemura, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704633/
https://www.ncbi.nlm.nih.gov/pubmed/36441681
http://dx.doi.org/10.1371/journal.pone.0277032