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Thymic involution caused by repeated cocaine administration includes apoptotic cell loss followed by ectopic adipogenesis
Cocaine abuse has a negative impact on the immune system. To investigate the adverse effects of binge cocaine administration on lymphoid organs such as thymus and spleen, we examined the effects of repeated intravenous (i.v.) administration of cocaine on rats. Sprague Dawley rats (male, 8 weeks old)...
Autores principales: | Unuma, Kana, Kaga, Homare, Funakoshi, Takeshi, Nomura, Moeka, Aki, Toshihiko, Uemura, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704633/ https://www.ncbi.nlm.nih.gov/pubmed/36441681 http://dx.doi.org/10.1371/journal.pone.0277032 |
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