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Molecular modelling of the HCMV IL-10 protein isoforms and analysis of their interaction with the human IL-10 receptor

The human cytomegalovirus (HCMV) UL111A gene encodes several homologs of the cellular interleukin 10 (cIL-10). Alternative splicing in the UL111A region produces two relatively well-characterized transcripts designated cmvIL-10 (isoform A) and LAcmvIL-10 (isoform B). The cmvIL-10 protein is the best...

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Detalles Bibliográficos
Autores principales: Pantaleão, Simone Queiroz, Camillo, Lívia de Moraes Bomediano, Neves, Tainan Cerqueira, Menezes, Isabela de Godoy, Stangherlin, Lucas Matheus, Batista, Helena Beatriz de Carvalho Ruthner, Poole, Emma, Nevels, Michael, Philot, Eric Alisson, Scott, Ana Ligia, Carlan da Silva, Maria Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704672/
https://www.ncbi.nlm.nih.gov/pubmed/36441804
http://dx.doi.org/10.1371/journal.pone.0277953