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Interference with LTβR signaling by tick saliva facilitates transmission of Lyme disease spirochetes

Lyme spirochetes have coevolved with ticks to optimize transmission to hosts using tick salivary molecules (TSMs) to counteract host defenses. TSMs modulate various molecular events at the tick–host interface. Lymphotoxin-beta receptor (LTβR) is a vital immune receptor and plays protective roles in...

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Detalles Bibliográficos
Autores principales: Jin, Lin, Jiang, Bao-Gui, Yin, Yizhu, Guo, Jingya, Jiang, Jia-Fu, Qi, Xiaopeng, Crispell, Gary, Karim, Shahid, Cao, Wu-Chun, Lai, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704693/
https://www.ncbi.nlm.nih.gov/pubmed/36383602
http://dx.doi.org/10.1073/pnas.2208274119