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Interference with LTβR signaling by tick saliva facilitates transmission of Lyme disease spirochetes
Lyme spirochetes have coevolved with ticks to optimize transmission to hosts using tick salivary molecules (TSMs) to counteract host defenses. TSMs modulate various molecular events at the tick–host interface. Lymphotoxin-beta receptor (LTβR) is a vital immune receptor and plays protective roles in...
Autores principales: | Jin, Lin, Jiang, Bao-Gui, Yin, Yizhu, Guo, Jingya, Jiang, Jia-Fu, Qi, Xiaopeng, Crispell, Gary, Karim, Shahid, Cao, Wu-Chun, Lai, Ren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704693/ https://www.ncbi.nlm.nih.gov/pubmed/36383602 http://dx.doi.org/10.1073/pnas.2208274119 |
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