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Lactate supply overtakes glucose when neural computational and cognitive loads scale up

Neural computational power is determined by neuroenergetics, but how and which energy substrates are allocated to various forms of memory engram is unclear. To solve this question, we asked whether neuronal fueling by glucose or lactate scales differently upon increasing neural computation and cogni...

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Detalles Bibliográficos
Autores principales: Dembitskaya, Yulia, Piette, Charlotte, Perez, Sylvie, Berry, Hugues, Magistretti, Pierre J., Venance, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704697/
https://www.ncbi.nlm.nih.gov/pubmed/36375086
http://dx.doi.org/10.1073/pnas.2212004119