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De novo sequencing and construction of a unique antibody for the recognition of alternative conformations of cytochrome c in cells
Cytochrome c (cyt c) can undergo reversible conformational changes under biologically relevant conditions. Revealing these alternative cyt c conformers at the cell and tissue level is challenging. A monoclonal antibody (mAb) identifying a key conformational change in cyt c was previously reported, b...
Autores principales: | Tomasina, Florencia, Martínez, Jennyfer, Zeida, Ari, Chiribao, María Laura, Demicheli, Verónica, Correa, Agustín, Quijano, Celia, Castro, Laura, Carnahan, Robert H., Vinson, Paige, Goff, Matt, Cooper, Tracy, McDonald, W. Hayes, Castellana, Natalie, Hannibal, Luciana, Morse, Paul T., Wan, Junmei, Hüttemann, Maik, Jemmerson, Ronald, Piacenza, Lucía, Radi, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704708/ https://www.ncbi.nlm.nih.gov/pubmed/36378644 http://dx.doi.org/10.1073/pnas.2213432119 |
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