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Anti-PF4 antibodies associated with disease severity in COVID-19

Severe COVID-19 is characterized by a prothrombotic state associated with thrombocytopenia, with microvascular thrombosis being almost invariably present in the lung and other organs at postmortem examination. We evaluated the presence of antibodies to platelet factor 4 (PF4)–polyanion complexes usi...

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Detalles Bibliográficos
Autores principales: Liu, Qingbo, Miao, Huiyi, Li, Shuai, Zhang, Peng, Gerber, Gloria F., Follmann, Dean, Ji, Hongkai, Zeger, Scott L., Chertow, Daniel S., Quinn, Thomas C., Robinson, Matthew L., Kickler, Thomas S., Rothman, Richard E., Fenstermacher, Katherine Z. J., Braunstein, Evan M., Cox, Andrea L., Farci, Patrizia, Fauci, Anthony S., Lusso, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704720/
https://www.ncbi.nlm.nih.gov/pubmed/36322776
http://dx.doi.org/10.1073/pnas.2213361119