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Anti-PF4 antibodies associated with disease severity in COVID-19
Severe COVID-19 is characterized by a prothrombotic state associated with thrombocytopenia, with microvascular thrombosis being almost invariably present in the lung and other organs at postmortem examination. We evaluated the presence of antibodies to platelet factor 4 (PF4)–polyanion complexes usi...
Autores principales: | Liu, Qingbo, Miao, Huiyi, Li, Shuai, Zhang, Peng, Gerber, Gloria F., Follmann, Dean, Ji, Hongkai, Zeger, Scott L., Chertow, Daniel S., Quinn, Thomas C., Robinson, Matthew L., Kickler, Thomas S., Rothman, Richard E., Fenstermacher, Katherine Z. J., Braunstein, Evan M., Cox, Andrea L., Farci, Patrizia, Fauci, Anthony S., Lusso, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704720/ https://www.ncbi.nlm.nih.gov/pubmed/36322776 http://dx.doi.org/10.1073/pnas.2213361119 |
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