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A Caenorhabditis elegans nck-1 and filamentous actin-regulating protein pathway mediates a key cellular defense against bacterial pore-forming proteins

Pore-forming proteins (PFPs) comprise the largest single class of bacterial protein virulence factors and are expressed by many human and animal bacterial pathogens. Cells that are attacked by these virulence factors activate epithelial intrinsic cellular defenses (or INCEDs) to prevent the attendan...

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Detalles Bibliográficos
Autores principales: Sitaram, Anand, Yin, Yunqiang, Zamaitis, Tammy, Zhang, Bo, Aroian, Raffi V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704757/
https://www.ncbi.nlm.nih.gov/pubmed/36374839
http://dx.doi.org/10.1371/journal.ppat.1010656