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A Caenorhabditis elegans nck-1 and filamentous actin-regulating protein pathway mediates a key cellular defense against bacterial pore-forming proteins
Pore-forming proteins (PFPs) comprise the largest single class of bacterial protein virulence factors and are expressed by many human and animal bacterial pathogens. Cells that are attacked by these virulence factors activate epithelial intrinsic cellular defenses (or INCEDs) to prevent the attendan...
Autores principales: | Sitaram, Anand, Yin, Yunqiang, Zamaitis, Tammy, Zhang, Bo, Aroian, Raffi V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704757/ https://www.ncbi.nlm.nih.gov/pubmed/36374839 http://dx.doi.org/10.1371/journal.ppat.1010656 |
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