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Mitochondrial ROS production by neutrophils is required for host antimicrobial function against Streptococcus pneumoniae and is controlled by A2B adenosine receptor signaling

Polymorphonuclear cells (PMNs) control Streptococcus pneumoniae (pneumococcus) infection through various antimicrobial activities. We previously found that reactive oxygen species (ROS) were required for optimal antibacterial function, however, the NADPH oxidase is known to be dispensable for the ab...

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Detalles Bibliográficos
Autores principales: Herring, Sydney E., Mao, Sovathiro, Bhalla, Manmeet, Tchalla, Essi Y. I., Kramer, Jill M., Bou Ghanem, Elsa N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704767/
https://www.ncbi.nlm.nih.gov/pubmed/36374941
http://dx.doi.org/10.1371/journal.ppat.1010700