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Mitochondrial ROS production by neutrophils is required for host antimicrobial function against Streptococcus pneumoniae and is controlled by A2B adenosine receptor signaling
Polymorphonuclear cells (PMNs) control Streptococcus pneumoniae (pneumococcus) infection through various antimicrobial activities. We previously found that reactive oxygen species (ROS) were required for optimal antibacterial function, however, the NADPH oxidase is known to be dispensable for the ab...
Autores principales: | Herring, Sydney E., Mao, Sovathiro, Bhalla, Manmeet, Tchalla, Essi Y. I., Kramer, Jill M., Bou Ghanem, Elsa N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704767/ https://www.ncbi.nlm.nih.gov/pubmed/36374941 http://dx.doi.org/10.1371/journal.ppat.1010700 |
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