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A single-cell analysis of thymopoiesis and thymic iNKT cell development in pigs

Many aspects of the porcine immune system remain poorly characterized, which poses a barrier to improving swine health and utilizing pigs as preclinical models. Here, we employ single-cell RNA sequencing (scRNA-seq) to create a cell atlas of the early-adolescent pig thymus. Our data show conserved f...

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Detalles Bibliográficos
Autores principales: Gu, Weihong, Madrid, Darling Melany C., Joyce, Sebastian, Driver, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704770/
https://www.ncbi.nlm.nih.gov/pubmed/35793622
http://dx.doi.org/10.1016/j.celrep.2022.111050