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LncRNA HOXA-AS2 Promotes Temozolomide Resistance in Glioblastoma by Regulated miR-302a-3p/IGF1 Axis

BACKGROUND: Glioblastoma (GBM) is a highly prevalent brain tumor characterized by high rates of morbidity, recurrence, and mortality. While temozolomide (TMZ) is commonly used as a first-line treatment for this cancer, the emergence of TMZ resistance limits its utility. The long noncoding RNA HOXA-A...

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Detalles Bibliográficos
Autores principales: Lin, Ligang, Lin, Da, Jin, Lingjiang, Wang, Junyou, Lin, Zheng, Zhang, Shuai, Lin, Gaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705095/
https://www.ncbi.nlm.nih.gov/pubmed/36479381
http://dx.doi.org/10.1155/2022/3941952