Vaccine protection by Cryptococcus neoformans Δsgl1 is mediated by γδ T cells via TLR2 signaling

We previously reported that administration of Cryptococcus neoformans Δsgl1 mutant vaccine, accumulating sterylglucosides (SGs) and having normal capsule (GXM), protects mice from a subsequent infection even during CD4(+) T cells deficiency, a condition commonly associated with cryptococcosis. Here,...

Descripción completa

Detalles Bibliográficos
Autores principales: Normile, Tyler G., Chu, Timothy H., Sheridan, Brian S., Del Poeta, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705245/
https://www.ncbi.nlm.nih.gov/pubmed/36229573
http://dx.doi.org/10.1038/s41385-022-00570-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705245/
https://www.ncbi.nlm.nih.gov/pubmed/36229573
http://dx.doi.org/10.1038/s41385-022-00570-3

Ejemplares similares