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Vaccine protection by Cryptococcus neoformans Δsgl1 is mediated by γδ T cells via TLR2 signaling
We previously reported that administration of Cryptococcus neoformans Δsgl1 mutant vaccine, accumulating sterylglucosides (SGs) and having normal capsule (GXM), protects mice from a subsequent infection even during CD4(+) T cells deficiency, a condition commonly associated with cryptococcosis. Here,...
Autores principales: | Normile, Tyler G., Chu, Timothy H., Sheridan, Brian S., Del Poeta, Maurizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705245/ https://www.ncbi.nlm.nih.gov/pubmed/36229573 http://dx.doi.org/10.1038/s41385-022-00570-3 |
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