Cargando…

Age-dependent rise in IFN-γ competence undermines effective type 2 responses to nematode infection

The efficient induction of type 2 immune responses is central to the control of helminth infections. Previous studies demonstrated that strong Th1 responses driven by intracellular pathogens as well as a bias for type 1 activity in senescent mice impedes the generation of Th2 responses and the contr...

Descripción completa

Detalles Bibliográficos
Autores principales: Kapse, Bhavya, Zhang, Hongwei, Affinass, Nicole, Ebner, Friederike, Hartmann, Susanne, Rausch, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705248/
https://www.ncbi.nlm.nih.gov/pubmed/35690651
http://dx.doi.org/10.1038/s41385-022-00519-6