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Age-dependent rise in IFN-γ competence undermines effective type 2 responses to nematode infection
The efficient induction of type 2 immune responses is central to the control of helminth infections. Previous studies demonstrated that strong Th1 responses driven by intracellular pathogens as well as a bias for type 1 activity in senescent mice impedes the generation of Th2 responses and the contr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705248/ https://www.ncbi.nlm.nih.gov/pubmed/35690651 http://dx.doi.org/10.1038/s41385-022-00519-6 |