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B-cell receptor physical properties affect relative IgG1 and IgE responses in mouse egg allergy

Mutated and unmutated IgE and IgG play different and partly opposing roles in allergy development, but the mechanisms controlling their relative production are incompletely understood. Here, we analyzed the IgE-response in murine food allergy. Deep sequencing of the complementary-determining region...

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Detalles Bibliográficos
Autores principales: Udoye, Christopher C., Rau, Christina N., Freye, Sarah M., Almeida, Larissa N., Vera-Cruz, Sarah, Othmer, Kai, Korkmaz, Rabia Ü., Clauder, Ann-Katrin, Lindemann, Timo, Niebuhr, Markus, Ott, Fabian, Kalies, Kathrin, Recke, Andreas, Busch, Hauke, Fähnrich, Anke, Finkelman, Fred D., Manz, Rudolf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705252/
https://www.ncbi.nlm.nih.gov/pubmed/36114245
http://dx.doi.org/10.1038/s41385-022-00567-y