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IκBζ controls IL-17-triggered gene expression program in intestinal epithelial cells that restricts colonization of SFB and prevents Th17-associated pathologies

Control of gut microbes is crucial for not only local defense in the intestine but also proper systemic immune responses. Although intestinal epithelial cells (IECs) play important roles in cytokine-mediated control of enterobacteria, the underlying mechanisms are not fully understood. Here we show...

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Detalles Bibliográficos
Autores principales: Yamazaki, Soh, Inohara, Naohiro, Ohmuraya, Masaki, Tsuneoka, Yousuke, Yagita, Hideo, Katagiri, Takaharu, Nishina, Takashi, Mikami, Tetuo, Funato, Hiromasa, Araki, Kimi, Nakano, Hiroyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705257/
https://www.ncbi.nlm.nih.gov/pubmed/35999460
http://dx.doi.org/10.1038/s41385-022-00554-3