Tissue-based IL-10 signalling in helminth infection limits IFNγ expression and promotes the intestinal Th2 response

Type 2 immunity is activated in response to both allergens and helminth infection. It can be detrimental or beneficial, and there is a pressing need to better understand its regulation. The immunosuppressive cytokine IL-10 is known as a T helper 2 (Th2) effector molecule, but it is currently unclear...

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Detalles Bibliográficos
Autores principales: Webster, Holly C., Gamino, Virginia, Andrusaite, Anna T., Ridgewell, Olivia J., McCowan, Jack, Shergold, Amy L., Heieis, Graham A., Milling, Simon W. F., Maizels, Rick M., Perona-Wright, Georgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705258/
https://www.ncbi.nlm.nih.gov/pubmed/35428872
http://dx.doi.org/10.1038/s41385-022-00513-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705258/
https://www.ncbi.nlm.nih.gov/pubmed/35428872
http://dx.doi.org/10.1038/s41385-022-00513-y

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