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Tissue-based IL-10 signalling in helminth infection limits IFNγ expression and promotes the intestinal Th2 response
Type 2 immunity is activated in response to both allergens and helminth infection. It can be detrimental or beneficial, and there is a pressing need to better understand its regulation. The immunosuppressive cytokine IL-10 is known as a T helper 2 (Th2) effector molecule, but it is currently unclear...
Autores principales: | Webster, Holly C., Gamino, Virginia, Andrusaite, Anna T., Ridgewell, Olivia J., McCowan, Jack, Shergold, Amy L., Heieis, Graham A., Milling, Simon W. F., Maizels, Rick M., Perona-Wright, Georgia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705258/ https://www.ncbi.nlm.nih.gov/pubmed/35428872 http://dx.doi.org/10.1038/s41385-022-00513-y |
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