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Epigenetic modulation enhances immunotherapy for pancreatic ductal adenocarcinoma

OBJECTIVES: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with a poor prognosis. PDAC has poor response to immunotherapy because of its unique tumour microenvironment (TME). In an attempt to stimulate immunologically silent pancreatic cancer, we investigated the role of epigenetic...

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Detalles Bibliográficos
Autores principales: Li, Yan, Hong, Young K, Wang, Xingtong, Pandit, Harshul, Zheng, Qianqian, Yu, Youxi, Shi, Xiaoju, Chen, Yujia, Tan, Min, Pulliam, Zachary, Bhutiani, Neal, Lin, Andrew, Badach, Jeremy, Zhang, Ping, Martin, Robert CG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705274/
https://www.ncbi.nlm.nih.gov/pubmed/36452477
http://dx.doi.org/10.1002/cti2.1430