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Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models
Type 2 diabetes mellitus is one of the most prevalent metabolic diseases presenting with systemic pathologies, including reproductive disorders in male diabetic patients. However, the molecular mechanisms that contributing to spermatogenesis dysfunction in diabetic patients have not yet been fully e...
Autores principales: | Song, Ke, Yang, Xinyan, An, Geng, Xia, Xinyu, Zhao, Jiexiang, Xu, Xiaoheng, Wan, Cong, Liu, Tianyuan, Zheng, Yi, Ren, Shaofang, Wang, Mei, Chang, Gang, Cronin, Shane J. F., Penninger, Josef M., Jing, Tao, Ou, Xianghong, Rao, Shuan, Liu, Zhaoting, Zhao, Xiao-Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705293/ https://www.ncbi.nlm.nih.gov/pubmed/36443325 http://dx.doi.org/10.1038/s41467-022-34990-3 |
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