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Chromatin accessibility dynamics dictate renal tubular epithelial cell response to injury

Renal tubular epithelial cells (TECs) can initiate an adaptive response to completely recover from mild acute kidney injury (AKI), whereas severe injury often leads to persistence of maladaptive repair and progression to kidney fibrosis. Through profiling of active DNA regulatory elements by ATAC-se...

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Detalles Bibliográficos
Autores principales: Cao, Xinyi, Wang, Jiuchen, Zhang, Tianye, Liu, Zhiheng, Liu, Lijun, Chen, Ying, Li, Zehua, Zhao, Youlu, Yu, Qi, Liu, Tong, Nie, Jing, Niu, Yuanjie, Chen, Yupeng, Yang, Li, Zhang, Lirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705299/
https://www.ncbi.nlm.nih.gov/pubmed/36443310
http://dx.doi.org/10.1038/s41467-022-34854-w