Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice

Secreted isoform of endoplasmic reticulum membrane complex subunit 10 (scEMC10) is a poorly characterized secreted protein of largely unknown physiological function. Here we demonstrate that scEMC10 is upregulated in people with obesity and is positively associated with insulin resistance. Consisten...

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Detalles Bibliográficos
Autores principales: Wang, Xuanchun, Li, Yanliang, Qiang, Guifen, Wang, Kaihua, Dai, Jiarong, McCann, Maximilian, Munoz, Marcos D., Gil, Victoria, Yu, Yifei, Li, Shengxian, Yang, Zhihong, Xu, Shanshan, Cordoba-Chacon, Jose, De Jesus, Dario F., Sun, Bei, Chen, Kuangyang, Wang, Yahao, Liu, Xiaoxia, Miao, Qing, Zhou, Linuo, Hu, Renming, Ding, Qiang, Kulkarni, Rohit N., Gao, Daming, Blüher, Matthias, Liew, Chong Wee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705309/
https://www.ncbi.nlm.nih.gov/pubmed/36443308
http://dx.doi.org/10.1038/s41467-022-34259-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705309/
https://www.ncbi.nlm.nih.gov/pubmed/36443308
http://dx.doi.org/10.1038/s41467-022-34259-9

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