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Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells

Ciclopirox (CPX), an antifungal drug, has recently been identified as a promising agent for cancer treatment. However, the effects and underlying mechanism of CPX as an antitumor agent of gastric cancer (GC) remain largely unknown. Here, we found that CPX dramatically suppresses GC xenograft growth...

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Detalles Bibliográficos
Autores principales: Chen, Lingyan, Chen, Dejian, Li, Jiwei, He, Lipeng, Chen, Ting, Song, Dandan, Shan, Shuang, Wang, Jiaxin, Lu, Xiaoang, Lu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705325/
https://www.ncbi.nlm.nih.gov/pubmed/36443287
http://dx.doi.org/10.1038/s41419-022-05456-7