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Current and future targeted alpha particle therapies for osteosarcoma: Radium-223, actinium-225, and thorium-227

Osteosarcoma is a high-grade sarcoma characterized by osteoid formation, nearly universal expression of IGF1R and with a subset expressing HER-2. These qualities provide opportunities for the use of the alpha particle-emitting isotopes to provide targeted radiation therapy via alpha particles precis...

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Detalles Bibliográficos
Autores principales: Anderson, Peter M., Subbiah, Vivek, Trucco, Matteo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705365/
https://www.ncbi.nlm.nih.gov/pubmed/36457575
http://dx.doi.org/10.3389/fmed.2022.1030094