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Pharmacokinetics of Morphine Sulfate Orodispersible Tablets and Bioequivalence with Immediate-Release Oral Morphine Sulfate Formulations in Healthy Adult Subjects Under Fasting Conditions: Single-Dose Comparative Bioavailability Studies

BACKGROUND AND OBJECTIVE: An orodispersible tablet (ODT) formulation of morphine sulfate has been developed to provide a novel alternative for patients with severe pain requiring opioids. This formulation has been developed in a range of doses (1–30 mg), enabling relief from severe pain to be achiev...

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Detalles Bibliográficos
Autores principales: Atrux-Tallau, Nicolas, Naimi, Zulaikha, Jaudinot, Eric-Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705466/
https://www.ncbi.nlm.nih.gov/pubmed/36331670
http://dx.doi.org/10.1007/s40261-022-01214-x