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A minimal-complexity light-sheet microscope maps network activity in 3D neuronal systems

In vitro systems mimicking brain regions, brain organoids, are revolutionizing the neuroscience field. However, characterization of their electrical activity has remained a challenge as it requires readout at millisecond timescale in 3D at single-neuron resolution. While custom-built microscopes use...

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Detalles Bibliográficos
Autores principales: Wysmolek, Paulina M., Kiessler, Filippo D., Salbaum, Katja A., Shelton, Elijah R., Sonntag, Selina M., Serwane, Friedhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705530/
https://www.ncbi.nlm.nih.gov/pubmed/36443413
http://dx.doi.org/10.1038/s41598-022-24350-y