Altered tRNA processing is linked to a distinct and unusual La protein in Tetrahymena thermophila

Nascent pre-tRNAs are transcribed by RNA polymerase III and immediately bound by La proteins on the UUU-3’OH sequence, using a tandem arrangement of the La motif and an adjacent RNA recognition motif-1 (RRM1), resulting in protection from 3’-exonucleases and promotion of pre-tRNA folding. The Tetrah...

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Detalles Bibliográficos
Autores principales: Kerkhofs, Kyra, Garg, Jyoti, Fafard-Couture, Étienne, Abou Elela, Sherif, Scott, Michelle S., Pearlman, Ronald E., Bayfield, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705548/
https://www.ncbi.nlm.nih.gov/pubmed/36443289
http://dx.doi.org/10.1038/s41467-022-34796-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705548/
https://www.ncbi.nlm.nih.gov/pubmed/36443289
http://dx.doi.org/10.1038/s41467-022-34796-3

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