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Active DNA damage response signaling initiates and maintains meiotic sex chromosome inactivation

Meiotic sex chromosome inactivation (MSCI) is an essential process in the male germline. While genetic experiments have established that the DNA damage response (DDR) pathway directs MSCI, due to limitations to the experimental systems available, mechanisms underlying MSCI remain largely unknown. He...

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Detalles Bibliográficos
Autores principales: Abe, Hironori, Yeh, Yu-Han, Munakata, Yasuhisa, Ishiguro, Kei-Ichiro, Andreassen, Paul R., Namekawa, Satoshi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705562/
https://www.ncbi.nlm.nih.gov/pubmed/36443288
http://dx.doi.org/10.1038/s41467-022-34295-5