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Active DNA damage response signaling initiates and maintains meiotic sex chromosome inactivation
Meiotic sex chromosome inactivation (MSCI) is an essential process in the male germline. While genetic experiments have established that the DNA damage response (DDR) pathway directs MSCI, due to limitations to the experimental systems available, mechanisms underlying MSCI remain largely unknown. He...
Autores principales: | Abe, Hironori, Yeh, Yu-Han, Munakata, Yasuhisa, Ishiguro, Kei-Ichiro, Andreassen, Paul R., Namekawa, Satoshi H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705562/ https://www.ncbi.nlm.nih.gov/pubmed/36443288 http://dx.doi.org/10.1038/s41467-022-34295-5 |
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