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Global perspectives on CYP2D6 associations with primaquine metabolism and Plasmodium vivax radical cure

Clinical trial and individual patient treatment outcomes have produced accumulating evidence that effective primaquine (PQ) treatment of Plasmodium vivax and P. ovale liver stage hypnozoites is associated with genetic variation in the human cytochrome P450 gene, CYP2D6. Successful PQ treatment of in...

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Detalles Bibliográficos
Autores principales: Olvany, Jasmine M., Williams, Scott M., Zimmerman, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705595/
https://www.ncbi.nlm.nih.gov/pubmed/36457706
http://dx.doi.org/10.3389/fphar.2022.752314