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Engineered Recombinant PON1-OPH Fusion Hybrids: Potentially Effective Catalytic Bioscavengers against Organophosphorus Nerve Agent Analogs

Organophosphorus nerve agents (OPNAs), including both G- and V-type nerve agents such as sarin, soman, tabun and VX, are extremely neurotoxic organophosphorus compounds. Catalytic bioscavengers capable of hydrolyzing OPNAs are under development because of the low protective effects and adverse side...

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Detalles Bibliográficos
Autores principales: Lee, Nari, Yun, Hyeongseok, Lee, Chan, Lee, Yikjae, Kim, Euna, Kim, Sumi, Jeon, Hyoeun, Yu, Chiho, Rho, Jaerang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Microbiology and Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705692/
https://www.ncbi.nlm.nih.gov/pubmed/33144547
http://dx.doi.org/10.4014/jmb.2006.06044