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Synthesis of activity evaluation of flavonoid derivatives as ɑ-glucosidase inhibitors

Six flavonoid derivatives were synthesized and tested for anti-α-glucosidase activities. All derivatives were confirmed using NMR and HRMS and exhibited excellent inhibitory effects on α-glucosidase. Derivative four exhibited the highest anti-α-glucosidase activity (IC(50): 15.71 ± 0.21 μM). Structu...

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Detalles Bibliográficos
Autores principales: Zhu, Hua, Zhong, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705736/
https://www.ncbi.nlm.nih.gov/pubmed/36458155
http://dx.doi.org/10.3389/fchem.2022.1041328