Mitochondrial Targeting Domain Homologs Induce Necrotic Cell Death Via Mitochondrial and Endoplasmic Reticulum Disruption

The mitochondrial targeting domain (MTD) of Noxa contributes to its mitochondrial localization and to apoptosis induction. As a peptide, MTD fused with octa-arginine (R8), a CPP, induces necrosis related to intracellular calcium influx and destruction of mitochondria and endoplasmic reticulum. We se...

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Detalles Bibliográficos
Autores principales: Park, Junghee, Han, Ji-Hye, Myung, Seung-Hyun, Chung, Hea-jong, Park, Jae-il, Cho, Ju-Yeon, Kim, Tae-Hyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Microbiology and Biotechnology 2021
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705834/
https://www.ncbi.nlm.nih.gov/pubmed/34024890
http://dx.doi.org/10.4014/jmb.2104.04021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705834/
https://www.ncbi.nlm.nih.gov/pubmed/34024890
http://dx.doi.org/10.4014/jmb.2104.04021

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