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Engineering of Biosynthesis Pathway and NADPH Supply for Improved L-5-Methyltetrahydrofolate Production by Lactococcus lactis

L-5-methyltetrahydrofolate (5-MTHF) is one of the biological active forms of folate, which is widely used as a nutraceutical. However, low yield and serious pollution associated with the chemical synthesis of 5-MTHF hampers its sustainable supply. In this study, 5-MTHF production was improved by eng...

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Detalles Bibliográficos
Autores principales: Lu, Chuanchuan, Liu, Yanfeng, Li, Jianghua, Liu, Long, Du, Guocheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Microbiology and Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705839/
https://www.ncbi.nlm.nih.gov/pubmed/31893598
http://dx.doi.org/10.4014/jmb.1910.10069